Neurodegeneration
Estrogen affects neuronal gene expression in primate prefrontal cortex
Published in Women's Health Weekly, July 8th, 2004
"Estrogen protects neurons from a variety of experimental insults in vitro and is thought to protect from acute and chronic neurodegenerative processes in vivo. Estrogen also enhances higher-level cognitive functions that are centered in the dorsolateral prefrontal cortex (DLPFC) in human and non-human primates," wrote J. Wang and colleagues.
"To investigate genomic mechanisms involved in estrogenic effects on the primate brain in vivo, we compared transcription factor mRNA and protein expression in...
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