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Reproductive Biology

Expression of CRH in placenta acts on gestational tissues in late pregnancy

Published in Women's Health Weekly, July 8th, 2004

Corticotrophin-releasing hormone (CRH) plays a role in parturition and researchers have revealed which tissues play the major role in labor control.

According to a recent study in the Journal of Molecular Endocrinology, "Increasing maternal plasma levels of corticotrophin-releasing hormone (CRH) during the last weeks of pregnancy suggest that this stress hormone plays an important role in the control of human parturition.

"Little is known about the quantitative contribution of gestational tissues (other than placenta) to intrauterine formation of CRH, urocortin and CRH-binding protein (CRH-BP), or about the distribution of CRH receptors within...

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