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Obstetrics

PCR detects primary CMV infection in seronegative pregnant women

Published in Women's Health Weekly, July 22nd, 2004

Serial maternal urine polymerase chain reaction can detect cytomegalovirus (CMV) infection in seronegative pregnant women, microbiologists report.

M. Khare and colleagues, Leicester Royal Infirmary, U.K., wanted "to determine if serial maternal urine polymerase chain reaction (PCR) tests can detect primary CMV infection during pregnancy. This was a prospective study conducted from 1 January 1999 to 31 December 1999 in an antenatal clinic setting of a teaching hospital. The study group included women who were CMV IgG [immunoglobulin G] negative and aged <30 years or had a pre-school child."

The researchers invited "the women ... to self-collect...

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