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Osteoporosis

Telomerized presenescent osteoblasts are able to correct bone loss

Published in Women's Health Weekly, July 22nd, 2004

Telomerized presenescent osteoblasts prevent bone mass loss in vivo, researchers report.

K. Yudoh and associates at St. Marianna University, Japan, wrote, "Previously, we showed that human osteoblasts expressing the human telomerase reverse transcriptase (hTERT) gene exhibited specific survival advantages - the result of breaching the replicative senescence barrier and maintaining the phenotypic and functional properties of primary osteoblasts in vitro over the total replicative capacity of primary osteoblasts."

In that study the researchers "postulated that rejuvenated osteoblasts may have a potential to correct bone loss or osteopenia in...

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