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Preeclampsia

Monoamine transporter gene expression compared in placentae

Published in Women's Health Weekly, July 29th, 2004

According to a study from Sweden, "Pre-eclampsia is one of the most common causes of perinatal and maternal morbidity and mortality. High blood pressure and proteinuria are important clinical signs of pre-eclampsia. Sympathetic overactivity and elevated level of circulating vaso active substances, such as monoamines has been shown.

"Extracellular concentrations of monoamines are normally kept low by specific transporter proteins of which many are expressed in the placenta."

B. Bottalico and colleagues, University of Lund Hospital, "used in situ hybridization and real-time PCR [polymerase chain reaction] to study the gene expression of monoamine...

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