Lipid Studies

NMR and GGE not necessarily interchangeable in women and diabetic patients

Published in Women's Health Weekly, August 5th, 2004

A study comparing agreement between nuclear magnetic resonance (NMR) and gradient gel electrophoresis (GGE) for measuring low-density lipoprotein (LDL) particle size found the two techniques are not necessarily interchangeable in women and patients with diabetes.

D.R. Witte and colleagues at the Royal Free & University College of London "measured LDL size by NMR and GGE in 324 individuals (152 with type 1 diabetes and 172 controls)."

They reported, "The Spearman correlation between both methods was 0.39 [95% confidence interval (CI)=0.29, 0.48]. The average difference was 5.38 nm (NMR being smaller), but it increased with increasing LDL size. Less...

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Source: Women's Health Weekly (2004-08-05)

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