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Aging

Researchers discover gene responsible for onset of infertility, cataracts

Published in Women's Health Weekly, August 5th, 2004

Mayo Clinic researchers have discovered a gene responsible for the onset of aging, including age-related disorders such as infertility, reproductive problems, and cataracts.

This research, conducted in genetically modified mice, is promising in helping physicians understand and treat the same disorders in humans. The findings appear in the July issue of Nature Genetics.

The discoveries came as the result of general investigations into possible genetic causes of cancer. In this case, it was discovered that this particular gene, called BubR1, governs production of a protein that modulates physical aging. The mice studied lacked normal levels of...

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