Adverse Drug Effects

High acetaminophen use, but not aspirin, NSAIDS, can impair renal function

Published in Women's Health Weekly, August 19th, 2004

According to Harvard Medical School researchers, women's long-term use of aspirin and nonsteroidal anti-inflammatory drugs does not adversely affect kidney function, but high use of acetaminophen possibly could.

Gary C. Curhan, MD, ScD, and colleagues gathered pertinent data from the Nurses' Health Study. "A total of 1,697 women participating in the Nurses' Health Study provided information on a mailed questionnaire in 1999 about lifetime use of acetaminophen, aspirin, and NSAIDs, and provided blood samples in 1989 and 2000," the researchers said.

"The main outcome was change in estimated glomerular filtration rate (GFR) in 11 years. Multivariate...

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Source: Women's Health Weekly (2004-08-19)

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