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Women's Health Weekly

Susan Hasty, Publisher

Table of Contents . . . September 2nd, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Women's Health Weekly | Other Publications

Breast Cancer - Telomere crisis is crucial stage in development of breast cancer

Hormone Replacement Therapy - Computer model: Short-term HRT improves QOL, decreases life expectancy

Hormone Replacement Therapy - Design of WHI design could not detect HRT cardioprotective effects

Obstetrics - Grant funds studies of clinical pharmacology in pregnant women

Tobacco Use - Nicotine therapy does not work as well for women as for men

Addiction Medicine - Mothers' prenatal cocaine use linked to behavior problems in boys

Asthma - Monitoring during pregnancy helps prevent serious exacerbations of asthma

Atherosclerosis - Circulating leptin associated with oxidized LDL in postmenopausal women

Autoimmune Diseases - Best management of myasthenia gravis in pregnancy uses team approach

Awards - U.S. NIH awards nearly $1.5 million for study of human bone precursor cells

Biochemistry - Changes in CD38/cADPR pathway may affect uterine motility and onset of labor

Biosynthesis - Biosynthesis of marmoset proteins occurs in oocytes and follicle cells

Blood Banking - Cord blood company initiates lawsuits to protect patent rights

Breast Cancer -  HER-2 amplification can be acquired with breast cancer progression

Breast Cancer - Bcl-2 antisense oligodeoxynucleotide chemosensitizes breast carcinoma cells

Breast Cancer - HER2 expression in metastases determined

Breast Cancer - Indole-3-carbinol augments IFN responsiveness in breast tumor cells

Breast Cancer - MIN-R EV mammography film wins R&D 100 Award

Breast Cancer - Murine study supports hypothesis that leptin may play role in tumorigenesis

Breast Cancer - New report says black women more likely to have deadly breast cancer tumors

Breast Cancer - Orphan drug designation granted from U.S. FDA for Efaproxyn

Breast Cancer - Upregulation of sst2 gene expression appears to indicate better prognosis

Breast Cancer - Utility of CISH in detecting HER-2/neu amplification evaluated

Breast Cancer - p53(Arg72Pro) polymorphism may be associated with ER+ risk in Japanese women

Breast Cancer Risk Factor - Link between dairy products and risk of breast cancer is weak

Breast Cancer Vaccine - Farnesyl transferase inhibitors show promise as therapies for breast cancer

Breast Cancer Vaccine - Peptides inducing immune responses in breast cancer patients identified

Breast Cancer Vaccine - Tamoxifen and soluble tumor-associated antigens suppress breast cancer

Breast Imaging - European patent granted for CT Laser Breast Imaging system

Breast Imaging - SecurViewDX breast imaging workstation receives FDA clearance

Breast Implants - 7-year deflation rate data filed for breast implants post approval survey study

Breast Implants - Long-term study in Danish women finds no disease link to silicone implants

Breast Implants - Tissue inhibitors of MMPs increased in women with capsular contracture

Breast Milk Banking - Ohio hospital close to establishing state's first breast milk bank

Breastfeeding - Public beliefs about breastfeeding policies in various settings

Breastfeeding - World Breastfeeding Week emphasized exclusive breastfeeding for first 6 months

Breastfeeding Trends - Most Louisiana mothers choose not to breastfeed, study shows

Business Update - Bioscience company retains McDermott Will & Emery

Cancer Therapy - Biotechnology company and ViroTarg sign anticancer license agreement

Cancer Therapy - Independent laboratory and Merck & Co., Inc., sign oncology research partnership

Cardiovascular Disease - Menopausal variations in cholesterol influenced by APOE genotype

Cardiovascular Disease - Systemic inflammation unrelated to pathogens associated with syndrome X

Caregiving - Working-age women who care for elderly parents risk of later poverty

Cellulite - Company reports unique mechanism of action for cellulite treatment

Cervical Cancer - HPV DNA subtype is prognostic factor in early stage disease

Cervical Cancer - Importance of HPV testing highlighted at meeting

Cervical Cancer - Laminin-5 gamma 2 chain expression facilitates detection of invasive lesions

Cervical Cancer - Mechanism described by which POU transcription factor represses growth in vitro

Cervical Cancer - Smoking, number of sex partners are epigenetic risk factors in NE Thailand

Contraception - Empowerment seen as ambiguous in case of female condom in North America

Cytomegalovirus - Advances made in diagnosis of maternal CMV infection

Cytomegalovirus - Gender differences exist in cytokine secretion from cytomegalovirus infection

Dementia - Changes in behavior may signal dementia, depression, or delirium in elderly

Developmental Biology - LBP-1a gene mutation linked to disruption of normal fetal development

Diabetes Survival & Mortality - Diabetes increases cancer mortality risk for some cancer types

Diagnostic Imaging - The glucose tracer FDG can't define breast cancer biology on PET

Diagnostics - Consensus opinion for mammography recalls reduces technicians' stress

Diagnostics - GTx collaborates to develop a diagnostic test to detect high-grade PIN

Diagnostics - Proteomics company files for patent, continues validation of NuroPro

Diet & Nutrition - Isoflavones in nursing rats' diet alter PR regulation by estrogen

Disease Prevention - Rat study: Perinatal pro-, antioxidant balance affects adulthood hypertension

Disease Prevention - Superoxide dismutase mimetic may be cardioprotective alternative to estrogen

Domestic Violence - History of violence a harbinger of increased sexual violence during pregnancy

Drug Delivery - Homing peptide complements the effects of antiangiogenic therapy in tumors

Emergency Contraception - Low doses of mifepristone or levonorgestrel appear to prevent or delay LH surge

Endocrinology - Estrogen suppression offers no protection to murine steatohepatitis models

Endocrinology - Eugonadal acromegalic females have higher BMD than general population

Endocrinology - Inappropriate treatment of women with persistent low hCG results is common

Endocrinology - Leptin-receptor genes stimulate the hypothalamo-pituitary-gonadal axis

Endocrinology - Parathyroid hormone assays for evaluation of bone loss need cautious reading

Endocrinology - Vaginal gene expression after neonatal DES exposure characterized

Endometrial Cancer - Some hormone therapy options can be considered after endometrial cancer

Finance - Contract medical procedure provider announces second quarter results

Finance - DOBI Medical International completes $5.16 million private placement

Finance - Imaging/diagnostics company reports increased revenues in Q3

Finance - Oncology-focused biopharma reports record product revenues Q2 2004

Finance - Provider of newborn and maternal-fetal care announces financial results

Fitness & Wellness - Sports icons lead campaign to get people 'Back in Full Swing' after heart attack

Food Safety - Danish health authorities ban some Kellogg products; company puzzled

Gene Transfer - Adenoviral vector containing tumor-specific constructs target ovarian cancer

Gene Transfer - Receptor-specific polyplexes pinpoint breast cancer cells

Genomics - Celera announces clinical milestone payment from Merck

Genomics - PRDM5 gene is silenced in human cancers and has growth-suppressive activities

Gynecologic Cancer - The nucleotide analog Fara-A inhibits angiogenic protein in ovarian cancer

Gynecology - Immunohistochemical staining helps diagnose endometrial Arias-Stella reaction

Gynecology - Neonatal estrogen exposure disrupts uterine development in postnatal sheep

HIV/AIDS - Women are forgotten HIV/AIDS patients in Zambia

HIV/AIDS Epidemiology - American Indians and Alaska natives surveilled for HIV/AIDS and risk behaviors

HIV/AIDS Epidemiology - Condom use reduces rate of new HIV infections in Thailand

HIV/AIDS Infection - Early HIV-1 diversity not restricted to certain risk groups/subtypes

HIV/AIDS Prevention - HIV prevention drug gets U.S. FDA clearance to advance in phase 1 clinical trial

Healthcare Coverage - Company reports Essure reimbursement grows to 149 million covered lives

Hormone Replacement Therapy - Estrogen and tamoxifen modulate cerebrovascular tone in ovariectomized rats

Hormone Replacement Therapy - Inhibitory effects of E2 and ZAL on tissue factor may afford cardioprotection

Human Papillomavirus - Pathogenic mechanisms of small cell carcinomas of uterine cervix vary

Hypothyroidism - Excess thyroid hormone harmful to fetus

Immunology - Fetal stem cells transfer to and remain in maternal bone and bone marrow

Infertility - Model attempts to provide overall prognosis with current treatments

Infertility - More research needed to expand treatment options

Infertility - National guidelines expected to promote ART best practices

Information Technology - Scientists at Canada's Robarts Research Institute model functioning human organs

Medical Equipment - State University of New York reports on infrared imaging to detect breast cancer

Nanomedicine - Report: Nanomedicine brings fresh hope to the medical world

Newborn Health - Report published on biomarkers for early diagnosis of intra-amniotic infection

Obesity Surgery - Deaths raise fears over stomach stapling

Obesity Therapy - Belief in controllability of weight affects perception of prejudice

Obstetrics - Anesthesia and acoustic stress-induced IUGR studied in mice

Obstetrics - Association found between miscarriage and presence of thyroid antibodies

Obstetrics - Case report: Impact of pregnancy on maternal hemodynamics underestimated

Obstetrics - Increased serum nitrite/nitrate adversely affects pregnancy outcome in rats

Obstetrics - Maternal folate deficiency at end of gestation associated with premature birth

Obstetrics - Once promising, fetal pulse oximetry questioned by many obstetricians

Obstetrics - Pelvic floor muscle training aids labor

Obstetrics - Pica during pregnancy has underestimated frequency

Obstetrics - Plasma tHcy during and after pregnancy studied relative to folate status

Obstetrics - Pregnancy in Autoimmune Polyglandular Syndrome Type 2 patient has good outcome

Obstetrics - Prenatal genetic testing for hemoglobinopathies is important

Obstetrics - Qualitative beta-hCG urine assays may be misleading in molar pregnancy

Obstetrics - Risk of venous thromboembolism is 5-6 times higher in pregnancy

Obstetrics - Study: Neonatal cranial sonography in an important quality control tool

Osteolysis - Case described of pubic bone post-fracture osteolysis simulating malignancy

Osteoporosis - BMD higher in young female dancers despite menstrual and diet problems

Osteoporosis - Chiropractic spinal manipulation not recommended in osteoporosis cases

Osteoporosis - Early adulthood gain in BMD seen in study of female U.S. Navy midshipmen

Osteoporosis - RUNX2 alleles associated with BMD in Scottish women

Ovarian Cancer - Maintaining normality, support are central care issues in chemotherapy

Ovarian Cancer - Sensitivity, specificity of MS-obtained proteomic diagnostic patterns compared

Ovarian Tumors - Gonadotropin levels higher in cancer tumor fluid than other tumor types

Papillomavirus - Genomic polymorphism of HPV type 52 predisposes toward persistent infection

Pelvic Organ Prolapse - Device firm reports early physician experience with bladder repair system

Personnel - Cerus appoints William J. Dawson as vice president, finance and CFO

Physiology - Gender differences in myogenic tone studied in murine model of oxidative stress

Phytotherapy - Phytoestrogens regulate genes in breast cancers that lack estrogen receptors

Polycystic Ovary Syndrome - Overweight/obesity appears to be cause of metabolic changes in PCOS patients

Preeclampsia - Impaired intercellular communication may cause deficient endovascular invasion

Preeclampsia - Neutrophil infiltration may explain smooth muscle dysfunction

Proteomics - Fingerprint protein identification is improved by combining many peak sets

Proteomics - Liquid chromatography quantitates a breast cancer resistance protein

Psoriatic Arthritis - E.U. CHMP recommends approval of REMICADE for PsA

Reproductive Biology - Cytokine receptor gp130 is hormonally regulated in human endometrium, decidua

Reproductive Biology - GH/IGF-I influences pituitary and gonadal functions

Reproductive Biology - The follicle-deplete mouse ovary produces androgen

Respiratory Medicine - Rhinitis in pregnancy best treated nonpharmacologically

Sexual & Reproductive Health - Brazilian government condom factory to begin operating next year

Sexual & Reproductive Health - New Virginia health campaign asks men a difficult question about sex

Sexually Transmitted Disease - North Carolina launching new safe sex project

Sexually Transmitted Diseases - Chlamydia-infected mouse oviduct epithelial cells elicit IL-12-p70 response

Stem Cell Research - Hematopoiesis can be viewed as a competitive exclusion process in females

Survival & Mortality - Health care program lowers child and maternal mortality in Bangladesh

Systemic Lupus Erythematosus -  Toxoplasma gondii infection inhibits lupus-like syndrome in autoimmune mice

Systemic Lupus Erythematosus - Extra precautions help make pregnancy safer for patients with lupus

Toxicology - Environmental cadmium may affect steroidogenesis

Traumatic Injury - Estrogen replacement boosts immune response in aged, injured mice

Urinary Incontinence - Preoperative statistic prognostic for TVT sling surgery outcome

Vulvar Cancer - Immunostaining for p16 distinguishes between HPV/non-HPV vulvar carcinomas

Women's Health - Health Secretary reminds mothers about the benefits of breastfeeding

Women's Health - Pharma society makes statement regarding emergency hormonal contraception

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