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Reproductive Immunology

Changes in decidual leukocyte distribution may be associated with labor

Published in Women's Health Weekly, September 30th, 2004

Study results suggest changes in decidual leukocyte distribution may be associated with labor.

A.P. Sindram-Trujillo and colleagues at Leiden University in The Netherlands compared "leukocyte populations in term decidua basalis and parietalis obtained after spontaneous vaginal delivery (SVD) or elective cesarean section (CS) without labor."

They collected "[d]ecidua basalis and parietalis samples . . . from placentas after SVD (n=20) and after CS (n=30). Following mechanical disaggregation, leukocytes were purified and stained with monoclonal antibodies. Percentages of leukocyte subclasses within the CD45+ cell fraction and activated T cells were...

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