Breast Cancer

Study finds some correlation between IGF-I levels and premenopausal cancer risk

Published in Women's Health Weekly, September 30th, 2004

According to researchers in Japan, "Biologic evidence suggests substantial effect of insulin-like growth factor (IGF)-I in mammary cell carcinogenesis. However, controversy remains regarding the association between circulating IGF-I levels and the risk of premenopausal breast cancer in epidemiologic studies.

"In addition, the association of IGF-binding protein (IGFBP)-3, which binds with and modifies the effect of IGF-I, is unclear."

A. Sugumar and colleagues at the Aichi Cancer Center conducted a meta-analysis to clarify the associations, but their findings did not draw a conclusive picture.

From the literature on Medline they...

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Source: Women's Health Weekly (2004-09-30)

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