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Gynecology

Membrane-bound peptidases are diagnostic markers for gynecological cancers

Published in Women's Health Weekly, October 14th, 2004

Membrane-bound peptidases are diagnostic markers for gynecological cancers.

"Membrane-bound peptidases play a key role in the control of growth, differentiation, and signal transduction of many cellular systems by degrading bioactive peptides. Thus, abnormal changes in their expression pattern and catalytic function result in altered peptide activation, which contributes to neoplastic transformation or progression," scientists in Japan report.

"In this review, we describe our recent findings along with work from other groups on the expression and biological functions of membrane-bound peptidases in cancer, focusing on the regulatory roles of three...

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