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Cancer Genetics

Computer program predicts women's genetic risk for breast and ovarian cancer

Published in Women's Health Weekly, November 4th, 2004

Cancer Research UK scientists have developed a computer program that can predict genetic susceptibility to breast and ovarian cancer with unprecedented accuracy.

The program, called BOADICEA (Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm), uses detailed family history to predict a woman's risk of developing cancer. It improves on previous programs because it takes into account genetic mutations besides those of the well-known BRCA1 and BRCA2 genes.

The researchers plan to offer BOADICEA to health professionals to help them pre-select women likely to be at high risk for further testing, and sparing others the...

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