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Systemic Lupus Erythematosus

Newly identified biomarkers could lead to quicker, better diagnosis of lupus

Published in Women's Health Weekly, November 25th, 2004

University of Pittsburgh researchers have identified biomarkers that could result in earlier and more accurate diagnosis of systemic lupus erythematosus (SLE), a devastating disease that affects as many as 1.5 million Americans, and occurs 10 to 15 times more frequently in women.

The results were published in the November 2004 issue of Arthritis & Rheumatism.

"This is the first report of abnormal levels of the protein erythrocyte-C4d in human disease," said lead author Susan Manzi, MD, MPH, associate professor of medicine, epidemiology, and dermatology at the University of Pittsburgh School of Medicine and the University of Pittsburgh Graduate...

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