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Breast Cancer

HER2-positive disease invades organs due to fatal chemical attraction

Published in Women's Health Weekly, December 9th, 2004

Researchers at The University of Texas M.D. Anderson Cancer Center have solved the mystery of why an aggressive form of HER2-positive breast cancer travels readily to a few key organs - lungs, liver, and bone -where it then establishes new tumors.

They say this finding may lead to strategies to block that deadly spread.

The study, published in the November 2004 issue of Cancer Cell, describes a lethal attraction between signals found on HER2-positive breast cancer cells and those on the surface of the organs - a magnetism that explains why this form of breast cancer, which affects up to 30% of patients, can be so invasive. The vast majority of...

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