Recurrent Spontaneous Abortion

Deficiency in immunosuppressing circulating factor may play role in RSA

Published in Women's Health Weekly, December 16th, 2004

According to a study from the United States, "Clinical evidence suggests that cell-mediated immunity is altered during pregnancy and that failure to suppress the maternal immune response can lead to placentation failure, resulting in partial or total rejection of the fetus.

"In contrast to women experiencing recurrent spontaneous abortions (RSA), normal uncomplicated pregnancies are associated decreased T-cell proliferation and production of Th1 cytokines and increased T-cell apoptosis," wrote D.D. Taylor and C. Gercel-Taylor, University of Louisville.

To investigate the role of a circulating factor present in normal pregnancy that may play an...

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Source: Women's Health Weekly (2004-12-16)

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