Women's Health Weekly
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Endometriosis
Gene polymorphism doesn't confer genetic susceptibility in Italian population
December 16th, 2004
DNA analysis has shown that the codon 72 polymorphism of the TP53 gene in a group of Italian women doesn't confer genetic susceptibility to endometriosis. Study authors D. Lattuada and colleagues wrote, "Endometriosis is a benign gynecologic disease that is associated with a certain risk for malignant degeneration. The disease has a genetic background, but the locations of possible genomic aberrations are still poorly clarified. "In this context, the proline form of TP53 codon 72 polymorphism has been recently associated with the risk of developing endometriosis. In this case-control study, we aimed to investigate further the potential association...
Source: Women's Health Weekly (2004-12-16)
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