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Fibromyalgia

Alpha(1)-antitrypsin replacement therapy controls FM symptoms in two sisters

Published in Women's Health Weekly, December 16th, 2004

When two sisters with alpha(1)-antitrypsin (AAT) deficiency and fibromyalgia (FM) were placed on AAT replacement therapy, their physicians noted that their FM symptoms were relieved and controlled.

After beginning commercial alpha(1)-antitrypsin infusions in 1992, both sisters "experienced a rapid, progressive, and constant control of their FM symptoms during the next 6 years (1992-98)," reported I. Blanco and colleagues, Hospital Valle Nalon, Asturias, Spain.

"However, in 1998, treatment of both patients was affected by the worldwide commercial shortage of AAT replacement therapy; replacement therapy infusions were halted for about 4-6 consecutive...

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