Women's Health Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Women's Health Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Breast Cancer
Autocrine Epo signaling inhibits hypoxia-induced apoptosis in cancer cells
December 23rd, 2004
According to a study from the United States, "Disordered perfusion and the resulting hypoxia are important features conferring tumor heterogeneity, which may contribute to relapse. "Hypoxic tumor cells have been associated with resistance both to radiation and to cytotoxic drugs. Hypoxia may also serve as a selection pressure in tumors by promoting apoptosis of some cells and expanding variants with decreased apoptotic potential, and thus play a role in the development of a more aggressive phenotype," wrote G. Acs and colleagues, University of Pennsylvania. "Erythropoietin (Epo), induced by hypoxia, controls erythropoiesis and plays a role in...
Source: Women's Health Weekly (2004-12-23)
|
