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Women's Health Weekly

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Cognitive Function



Executive function is less sensitive to estradiol than spatial memory



December 23rd, 2004

Experiments with rhesus monkeys show that executive processes, handled by the brain's frontal lobes, are less sensitive to estradiol than spatial memory, which depends on input from the hippocampus.

"Functions supported by the frontal lobes are particularly sensitive to the detrimental effects of aging. Recent studies on postmenopausal women find that estrogen replacement therapy benefits performance on tasks dependent on the frontal lobes," wrote A. Lacreuse and colleagues at Emory University, Atlanta, Georgia.

"To determine whether estrogen has a similar influence in a rhesus monkey model of menopause, we tested five aged, long-term ovariectomized...


Source: Women's Health Weekly (2004-12-23)

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