Women's Health Weekly
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Disease Prevention
Drug delivery system with EDTA is safe intravaginal barrier device
December 23rd, 2004
A female-controlled drug delivery system (FcDDS) containing sodium dodecyl sulfate as a microbicide, ethylenediaminetetraacetic acid (EDTA) as a synergistic microbicide, and lactic acid as a pH modulator is biocompatible and a safe intravaginal barrier device against sexually transmitted diseases, University of Missouri pharmaceutical researchers report. B.K. Warrier and colleagues evaluated "the host response of the vagina to the FcDDS . . . through biocompatibility tests including cell viability, estrogenicity, and cytotoxicity assays on HeLa cervical cells and NIH:Ovcar-3 ovarian cells. Gel electrophoresis and reverse transcriptase polymerase chain reaction assays on...
Source: Women's Health Weekly (2004-12-23)
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