Women's Health Weekly
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Endocrinology
FFAs may be involved in enhanced circadian ACTH release in obese women
December 23rd, 2004
Free fatty acids may be involved in the enhanced circadian release of adrenocorticotropin hormone seen in obese women, researchers suggest. "Several studies suggest that the hypothalamo-pituitary-adrenal (HPA) axis is exceedingly active in obese individuals. Experimental studies show that circulating free fatty acids (FFAs) promote the secretory activity of the HPA axis and that human obesity is associated with high circulating FFAs," wrote P. Kok and colleagues, Leiden University, the Netherlands. These researchers tested the hypothesis "that HPA axis activity is enhanced and that lowering of circulating FFAs by acipimox would reduce spontaneous...
Source: Women's Health Weekly (2004-12-23)
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