Women's Health Weekly
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Female Diabetes
PPAR-gamma activation affects nitric oxide production in placenta
December 23rd, 2004
Peroxisome proliferator-activated receptor (PPAR) gamma activation by its endogenous ligand 15-deoxy Delta12,14 prostaglandin J2 influences nitric oxide production in term placental tissues from diabetic women. According to recent research from Argentina, "Diabetes induces alterations which condition placental remodeling. The levels of nitric oxide (NO) (a modulator of placental invasiveness, differentiation and proliferation) were higher in term placental explants from diabetic patients when compared to controls. Peroxisome proliferator-activated receptor gamma (PPAR-gamma) activation by its endogenous ligand 15-deoxy Delta12,14...
Source: Women's Health Weekly (2004-12-23)
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