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Women's Health Weekly

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Cervical Cancer



HPV genotyping of high-grade SIL may have prognostic value



December 30th, 2004

Human papillomavirus (HPV) genotyping of high grade squamous intraepithelial cervical lesions may help determine risk of progression to invasive carcinoma.

"High-grade squamous intraepithelial lesions of the cervix are heterogeneous in their invasive potential. Comparison of human papillomavirus types between invasive cervical carcinoma and high-grade squamous dysplasia may provide insight into this biological variability," said R.E. Zuna and colleagues, University of Oklahoma.

This team analyzed "liquid-based Pap specimens from 55 high-grade intraepithelial lesions and 47 invasive cervical carcinomas ... by reverse line blot for 27 human...


Source: Women's Health Weekly (2004-12-30)

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