Women's Health Weekly
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Arthritis
In rats arthritis suppresses bone formation induced by mechanical loading
December 30th, 2004
A small study conducted in adult female rats found that arthritis suppressed the bone formation induced by mechanical loading. Y. Kameyama from Tottori University, Japan, and colleagues used a rat model of collagen-induced arthritis (CIA) to study the effects of inflammation on the response of bone to mechanical stress. "Six-month-old female Wistar rats were used in the experiment. Bovine type 11 collagen sensitization and additional sensitization after 1 week were performed in all CIA groups," according to the researchers. "Loads were applied using a four-point bending device. The right tibia was loaded in both CIA and control...
Source: Women's Health Weekly (2004-12-30)
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