Women's Health Weekly
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Breast Cancer
COMT-L allele and COMT-LL genotype are risk factors in Turkish women
January 6th, 2005
Researchers have determined that the COMT-L allele and COMT-LL genotype are risk factors for breast cancer development in Turkish women. "There is compelling evidence to suggest that catecholestrogens may play a role in the development of breast cancer. Particularly, inactivation of catecholestrogens may prevent the genesis and arrest the development of breast cancer. Catechol-O-methyltransferase (COMT) is polymorphic and responsible for the detoxification of catecholestrogens," wrote A. Sazci and colleagues, University of Kocaeli, Turkey. They studied "what role COMT gene polymorphisms may play in the development of breast cancer in a case-control...
Source: Women's Health Weekly (2005-01-06)
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