Women's Health Weekly
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Breast Cancer
Loss of Syk expression is progressive during breast tumor development
January 6th, 2005
Loss of Syk expression is progressive during breast tumor development. According to a study from the United States, "The tumor suppressor gene Syk tyrosine kinase is absent or reduced in invasive breast cancer tissues and cell lines; its loss in breast tissues is linked to poor prognosis and metastasis. "Also, evidence shows that in vitro Syk is involved in regulating proliferation. Here, we show by in situ hybridization on breast tissue sections that the loss of Syk expression is progressive during tumor development." "Strikingly," wrote M. Moroni and colleagues, "Syk is already partially lost in normal epithelial tissue adjacent...
Source: Women's Health Weekly (2005-01-06)
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