Women's Health Weekly
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Breast Cancer Therapy
Tamoxifen does not prevent mobilization of body lipids
January 6th, 2005
Tamoxifen does not prevent the mobilization of body lipids elicited by oleoyl-estrone. According to recent research published in the journal Steroids, "Oleoyl-estrone is a powerful, shunning adipose tissue-derived signal that has biological effects widely opposed to those of its estrone moiety. The present experiment was designed to determine whether oleoyl-estrone effects on body energy are mediated by the estrogen receptor, blocked with the antagonist tamoxifen. Male Wistar rats were given daily oral doses of 10 micromole/kg d of oleoyl-estrone in oil containing 0 or 0.40 mg/kg per day of tamoxifen." "The data were compared with controls...
Source: Women's Health Weekly (2005-01-06)
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