Women's Health Weekly
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Women's Health Weekly
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Cancer Genomics and Genetics
Tumor suppressor BRCA1 protects cells from oxidative stress
January 6th, 2005
The tumor suppressor gene BRCA1 helps protects cells from oxidative stress. "Mutations of the breast cancer susceptibility gene 1 (BRCA1)" confer an "increased risk for breast, ovarian, and prostate cancers," researchers in the United States explained. "To investigate the function of the BRCA1 gene," I. Bae and colleagues at Georgetown University "performed DNA microarray and confirmatory reverse transcription-PCR analyses to identify BRCA1-regulated gene expression changes." BRCA1 "upregulates the expression of multiple genes involved in the cytoprotective antioxidant response, including glutathione S-transferases,...
Source: Women's Health Weekly (2005-01-06)
|
