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Women's Health Weekly

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Hypertension



eNOS gene may influence predisposition to high blood pressure in females



January 6th, 2005

The endothelial nitric oxide synthase gene may play a role in predisposing females to hypertension.

"Impaired endothelial function caused by decreased nitric oxide (NO) production plays a pathophysiologic role in essential hypertension. Although cross-sectional data are available on the association between endothelial NO synthase gene polymorphisms and hypertension, whether the gene variants and their haplotypes affect the long-term cumulative burden and trend of blood pressure since childhood is not known," said W. Chen and colleagues, Tulane Center for Cardiovascular Health, New Orleans.

They studied this "using four polymorphisms and a...


Source: Women's Health Weekly (2005-01-06)

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