Women's Health Weekly
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Collagen
Cell clump formation analyzed, cementing by collagen fibrils revealed
January 6th, 2005
According to a study from Japan, reconstituted type V collagen fibrils can be used as cementing materials in the formation of cell clumps in culture. "Previous studies have reported that type V collagen is an anti-adhesive substrate for cultured cells in that the cells detach from culture dishes coated with type V collagen molecules or polypeptides derived from them," wrote T. Kihara and colleagues, University of Tokyo. "We have noticed that human fetal lung fibroblasts (TIG-1) initially show no reduction in adherence to and spreading on a dish coated with reconstituted type V collagen fibrils but eventually detach from the dish and form cell clumps. ...
Source: Women's Health Weekly (2005-01-06)
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