Proteomics
Vascular gene expression is altered in invasive breast carcinoma
Published in Women's Health Weekly, January 13th, 2005
According to published research from the United States, "the molecular signature that defines tumor microvasculature will likely provide clues as to how vascular-dependent tumor proliferation is regulated. Using purified endothelial cells, we generated a database of gene expression changes accompanying vascular proliferation in invasive breast cancer."
"In contrast to normal mammary vasculature, invasive breast cancer vasculature expresses extracellular matrix and surface proteins characteristic of proliferating and migrating endothelial cells," B.S. Parker and colleagues, Genzyme...
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