Women's Health Weekly
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Breast Cancer
Effect of EGF gradient profile on tumor cell chemotaxis determined
January 13th, 2005
The effects of epidermal growth factor (EGF) gradients on breast tumor cell chemotaxis have been characterized. "Chemotaxis, directed cell migration in a gradient of chemoattractant, is an important biological phenomenon that plays pivotal roles in cancer metastasis," researchers in the United States explained. In a recent study conducted by S.J. Wang and coauthors at the University of California-Irvine, "[n]ewly developed microfluidic chemotaxis chambers (MCC) were used" to evaluate "chemotaxis of metastatic breast cancer cells, MDA-MB-231, in EGF gradients of well-defined profiles." "Migration behaviors of MDA-MB-231 cells in...
Source: Women's Health Weekly (2005-01-13)
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