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Women's Health Weekly

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Cancer Chemotherapy



In vitro study results presented for premetrexed/paclitaxel regimen



January 13th, 2005

Scientists in Japan recently presented results of their in vitro study on the combination of premetrexed and paclitaxel in human carcinoma cell lines.

"Pemetrexed is a novel multitargeted antifolate with significant clinical activity against a variety of tumors. We studied the schedule-dependent cytotoxic effects of pemetrexed in combination with paclitaxel in vitro to improve our understanding of how this combination might be used clinically," reported Y. Kano and colleagues, Tochigi Cancer Center.

"Human lung cancer A549 cells, breast cancer MCF7, ovarian cancer PA1, and colon cancer WiDr cells were exposed to both pemetrexed and paclitaxel in...


Source: Women's Health Weekly (2005-01-13)

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