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Bone Health
Affects of excess fluoride can result in reduced calcium absorption
January 13th, 2005
Excess fluoride was found to reduce mRNA expression of calcium-sensing receptor, vitamin D receptor, and calbindin D 9 k in rats, and this, in turn, resulted in less calcium absorption. As the molecular basis of fluoride-induced reduction of intestinal calcium absorption hadn't been investigated, S. Tiwari and colleagues at the Sanjay Gandhi Postgraduate Institute of Medical Science, Uttar Pradesh, "studied the mRNA expression of calcium-sensing receptor (CaR), vitamin D receptor (VDR) and calbindin D 9 k (D 9 k) by Northern blot analysis in the duodenal mucosa of rats." According to the researchers' report, "Weanling pups fed with chow diet...
Source: Women's Health Weekly (2005-01-13)
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