Women's Health Weekly
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Chronic Kidney Disease
Oral estradiol dose for postmenopausal women with CKD should be cut 50% or more
January 20th, 2005
The oral estradiol dose for postmenopausal women with chronic kidney disease (CKD) should be reduced by at least 50%, researchers recommend. "Estradiol, estrone, and estrone sulfate are the primary circulating estrogens in women; the relative amounts depend on the menopausal status of the women. Administration of oral estradiol or conjugated equine estrogens (CEE) results in a high ratio of estrone to estradiol, whereas use of non-oral routes (dermal, vaginal, or parenteral) results in approximately equal plasma concentrations of estradiol and estrone," explained G.D. Anderson and colleagues, University of Washington. Although estradiol and estrone...
Source: Women's Health Weekly (2005-01-20)
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