Women's Health Weekly
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Breast Cancer
Premenopausal status and combined effect of three genotypes increases risk
January 20th, 2005
Premenopausal status plus the combined effect of the catechol O-methyl transferase and two glutathione S-transferase genotypes increases the risk of developing breast cancer, according to a study from South Korea. S.K. Park and colleagues, Seoul National University, wrote, "Our previous studies suggested that both catechol O-methyl transferase (COMT) and glutathione S-transferase (GST) M1 and T1 genotypes are associated with breast cancer risk. Here we extended the studies to evaluate the potential combined effect of these genotypes in individual breast cancer risk." "Incident breast cancer cases (n=202) and controls (n=299) with no previous cancer...
Source: Women's Health Weekly (2005-01-20)
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