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Women's Health Weekly

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Drug Development



Zoledronic acid prevents bone loss in hormone-treated breast cancer patients



January 20th, 2005

Zoledronic acid prevents loss of bone mass caused by adjuvant treatment with an aromatase inhibitor or tamoxifen and the luteinising hormone-releasing hormone analog (LHRHa) goserelin in premenopausal women with early-stage hormone receptor-positive breast cancers. This new clinical finding was presented at the annual San Antonio Breast Cancer Symposium.

For the first time, a large multicenter clinical trial has shown how to prevent cancer treatment-induced bone loss (CTIBL) and established that such bone loss is a frequent side effect of hormonal therapy for breast cancer in premenopausal women. The study is sponsored by the Austrian Breast and Colorectal Cancer Study...


Source: Women's Health Weekly (2005-01-20)

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