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Women's Health Weekly

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Endocrinology



Roles of activin and inhibin in the human breast studied



January 20th, 2005

According to a study from Brazil, "Activins and inhibins are growth factors involved in cell differentiation and proliferation. Human breast tissues such as normal mammary tissue, fibroadenoma, and breast cancer express inhibin and activin mRNA and proteins. Activin A and its binding protein, follistatin, are also present in human milk during the first week of lactation."

F.M. Reis and colleagues at the University Federal de Minas Gerais used immunohistochemistry techniques to observe "that the inhibin/activin alpha, betaA, and betaB subunits are present in normal breast tissue regardless of menstrual cycle phase or menopause, as well as in fibrocystic disease, and...


Source: Women's Health Weekly (2005-01-20)

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