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Women's Health Weekly

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Apoptosis



Apoptosis analyzed, resistance in regenerating hepatocytes demonstrated



January 27th, 2005

Research from Spain published in the Journal of Cellular Physiology documented the resistance to induced apoptosis in regenerating hepatocytes.

"Treatment with transforming growth factor beta (TGF-beta) of hepatocytes from two different proliferative conditions, such as fetal development and adult liver regeneration, shows that regenerating cells respond to this cytokine in terms of growth inhibition, but are less sensitive than the fetal ones to the apoptosis induced by this factor.

"Regenerating TGF-beta treated cells show higher cell viability and lower percentage of apoptotic cells than the fetal treated ones. Furthermore, TGF-beta treated...


Source: Women's Health Weekly (2005-01-27)

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