Women's Health Weekly
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Assisted Reproduction
Growth differentiation factor gene fragments treat porcine ovarian dysfunction
January 27th, 2005
Growth differentiation factor gene fragments treat porcine ovarian dysfunction. According to published research from Japan, "growth differentiation factor-9 (GDF-9) is a growth factor secreted by oocytes in growing ovarian follicles. To investigate the ovarian function of GDF-9 in pigs, we first cloned porcine GDF-9 complementary DNA (cDNA), and then injected its gene fragments into the ovary in gilts. Porcine GDF-9 has open reading frame (ORF) homologies of 81.4%, 84.6%, 84.2%, 72.7% and 72.6% with its human, bovine, ovine, rat and mouse counterparts respectively." "Regarding the deduced amino-acid sequence of the mature protein, the corresponding...
Source: Women's Health Weekly (2005-01-27)
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