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Women's Health Weekly

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Birth Defects



Maternal nutritional status affects fetal risk of developing orofacial cleft



January 27th, 2005

According to recent research from the Netherlands, Periconceptional folate and folic acid intake prevents orofacial clefts (OFC) in the offspring. It has been suggested that other nutrients also play a role.

"We investigated the preconceptional intake of macronutrients (protein, fat, carbohydrate, fiber, and cholesterol), vitamins (vitamin A, retinol, beta-carotene, ascorbic acid, and a-tocopherol), minerals (calcium, phosphorus, iron, magnesium, and zinc), and food groups in mothers of OFC children and controls," reported I.P.C. Krapels and colleagues, University of Nijmegen.

"At about 14 months after the index pregnancy, 206 mothers of a child with...


Source: Women's Health Weekly (2005-01-27)

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