Women's Health Weekly
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Carcinogenesis
Reports describe recent advances in carcinogenesis research
January 27th, 2005
Data on carcinogenesis are outlined in reports from Malaysia, Taiwan and the People's Republic of China. Study 1: Researchers in Malaysia have identified in a mouse model apoptosis-associated genes regulated in response to diethylstilbestrol (DES). "Studies with clastogenic carcinogen diethylstilbestrol resulted in a broad of spectrum of toxic and carcinogenic effects in humans and rodents, but the cellular and molecular mechanism(s) by which it induces cancer is not clear. To identify putative genetic targets for p53 in vivo, we applied the cDNA macroarray gene expression profiles associated with apoptosis by comparing p53+/- knockout mice and...
Source: Women's Health Weekly (2005-01-27)
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