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Women's Health Weekly

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Chlamydia trachomatis



Hematopoietic cells needed to initiate specific CD8+ T-cell response



January 27th, 2005

Hematopoietic cells are necessary to initiate a Chlamydia trachomatis-specific CD8+ T-cell response, researchers report.

"Chlamydia trachomatis is a global human pathogen causing diseases ranging from blinding trachoma to pelvic inflammatory disease. To explore how innate and adaptive immune responses cooperate to protect against systemic infection with C. trachomatis L2, we investigated the role of macrophages (Mphi) and dendritic cells (DCs) in the stimulation of C. trachomatis-specific CD8+ T cells," wrote L.N. Steele and colleagues, Harvard University.

The researchers found that "C. trachomatis infection of Mphi...


Source: Women's Health Weekly (2005-01-27)

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