Women's Health Weekly
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Addiction Medicine
Ghrelin and glucagon-like peptide studied, role of cannabinoids revealed
January 27th, 2005
According to recent research from Begium published in the British Journal of Nutrition, plasma ghrelin and a glucagon-like peptide may be modulated by two anorexigenic cannabinoid compounds. "The CB1 cannabinoid receptor antagonist, N-piperidino-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxamide (Rimonabant; SR141716A), and oleoylethanolamide (OEA) are known to reduce food consumption, by, at least partially, a peripheral regulation of feeding. The effects of systemic SR141716A or OEA (5 mg/kg) administrations on food consumption in 24 h food-deprived and fed rats were investigated. "In fasted rats, SR141716A and OEA...
Source: Women's Health Weekly (2005-01-27)
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