Drug Development

Investigational new drug application submitted for cancer candidate

Published in Women's Health Weekly, January 27th, 2005

Myriad Genetics, Inc., (NASDAQ:MYGN) announced that it has submitted an investigational new drug (IND) application to the U.S. Food and Drug Administration (FDA) to begin a phase I human clinical trial with MPC-2130 (previously referred to as MPI-176716), a broad-acting inducer of apoptosis in cancer cells.

The phase I clinical study is designed to evaluate the safety and pharmacokinetic profile of MPC-2130 in patients with advanced metastatic tumors or blood cancers as well as refractory cancer that has progressed despite previous chemotherapy. In preclinical studies MPC-2130 has demonstrated significant cancer cell killing activity in ovarian cancer, prostate cancer...

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Source: Women's Health Weekly (2005-01-27)

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