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Bone

Low iron negatively affects rat bone independently of energy intake, weight

Published in Women's Health Weekly, February 3rd, 2005

Iron deficiency in rats negatively affected bone mineral density and content of their vertebrae and femurs independently of energy intake and weight, Kansas State University researchers reported.

"The question of whether iron deficiency has direct adverse effects on vertebral trabecular bone and long bones was answered by this study," D.M. Medeiros and colleagues stated.

"Four groups of female weanling rats were fed for 5 weeks diets that were 1) control; 2) calcium restricted, 1.0 g Ca/kg diet; 3) iron deficient, <8 mg Fe/kg diet; or 4) control, pair-fed to the iron-deficient group," according to the study report.

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