Published in Women's Health Weekly, February 3rd, 2005
According to scientists in Switzerland, "Palonosetron (Aloxi, Onicit) is a potent, single stereoisomeric 5-HT3 receptor antagonist developed to prevent chemotherapy-induced nausea and vomiting. The pharmacokinetics and metabolic disposition of a single intravenous [14C]-palonosetron (10 mcg/kg, 0.8 mcCi/kg) bolus dose were evaluated in six healthy volunteers (three males, three females) using serial blood, plasma, urine and fecal samples obtained over 10 days. The safety, tolerability and cardiac...
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