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Women's Health Weekly

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Adverse Drug Reaction



Common antidepressants lower effects of tamoxifen in many women



February 10th, 2005

Clinical trial data confirm that selective serotonin reuptake inhibitor antidepressants reduce the effects of tamoxifen in many breast cancer patients.

The trial results were published by researchers from the Indiana University School of Medicine, the University of Michigan, and Johns Hopkins University in the January 5, 2005, issue of the Journal of the National Cancer Institute.

The large clinical trial confirmed data from an earlier study showing that selective serotonin reuptake inhibitor (SSRI) antidepressants may hinder the effectiveness of tamoxifen, a drug commonly administered to breast cancer patients. The study also reported that...


Source: Women's Health Weekly (2005-02-10)

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