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Women's Health Weekly

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Cancer Genetics



Long-term OC use reduces ovarian cancer risk among BRCA1/2 carriers



February 10th, 2005

Recent study data provide more evidence that long-term use of oral contraceptives reduces the risk of ovarian cancer among women who carry the BRCA 1 or BRCA 2 gene mutations.

"Women with mutations of the genes BRCA1 or BRCA2 are at increased risk of ovarian cancer. Oral contraceptives protect against ovarian cancer in general, but it is not known whether they protect against the disease in carriers of these mutations," said A.S. Whittemore and colleagues, Stanford University.

"We obtained self-reported lifetime histories of oral contraceptive use from 451 women who carried mutations of BRCA1 or BRCA2," they continued. "We used conditional logistic...


Source: Women's Health Weekly (2005-02-10)

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